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Bariatric Surgery »  Meet the Team »  Research Faculty »  Anne Schafer, M.D.
Anne Schafer, M.D.

Anne Schafer, M.D.

  • Assistant Professor Department of Medicine - VAMC

Contact Information

4150 Clement Street
San Francisco CA 94121
Phone 415-221-4810x4895
[email protected]
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Education

UCSF School of Medicine, M.D., 2004 

Residencies

  • Internal Medicine, UCSF

Board Certifications

  • American Board of Internal Medicine - General
  • American Board of Internal Medicine, Endocrinology, Diabetes and Metabolism Subspecialty

Program Affiliations

  • UCSF Department of Medicine
  • UCSF Bariatric Surgery Program
  • SF VAMC

Research Interests

  • Dr. Schafer is Assistant Professor of Medicine and of Epidemiology & Biostatistics at UCSF and a practicing endocrinologist at the San Francisco VA Medical Center. She is board-certified in by the American Board of Internal Medicine in Internal Medicine and by the American Board of Internal Medicine in Endocrinology, Diabetes and Metabolism Subspecialty.

Biography

Dr. Schafer is Professor of Medicine and of Epidemiology & Biostatistics at UCSF and Chief of Endocrinology and Metabolism at the San Francisco VA Health Care System. She is board-certified by the American Board of Internal Medicine in the subspecialty of Endocrinology, Diabetes and Metabolism. Her research focus is osteoporosis and bone metabolism. One of her research emphases is osteoporosis treatment and the assessment of response to osteoporosis therapy. She also studies the relationships between bone, fat, and glucose metabolism, including the effects of obesity and diabetes on bone, and the skeletal regulation of energy metabolism. This research program includes investigations of the effects of bariatric surgery (weight loss surgery) on calcium metabolism and skeletal health. Dr. Schafer's research has been funded by the National Institutes of Health, the US Department of Veterans Affairs, and the American Society for Bone and Mineral Research.

Research Overview

Her research focus is on osteoporosis and metabolic bone disease. One of her specific research emphases is osteoporosis treatment and the assessment of response to osteoporosis therapy. Pharmacologic treatment for osteoporosis may involve the use of an antiresorptive agent (one that decreases bone resorption) or an anabolic agent (one that stimulates bone formation). Dr. Schafer and colleagues conducted a randomized, placebo-controlled trial testing two innovative combinations of concurrent and sequential anabolic and anti-resorptive therapy in postmenopausal women with low bone mass. Findings from the trial may help to expand treatment options for osteoporosis. Additionally, Dr. Schafer is actively engaged in research involving the relationship between bone and fat. Bone-fat interplay—including the effects of fat on bone metabolism and the skeletal regulation of energy metabolism—is an area of increasing investigation. Currently, she is studying the effects of bariatric surgery (surgical weight loss) on calcium metabolism and skeletal health. Her research is funded by the U.S. Department of Veterans Affairs, the National Institutes of Health (National Institute on Diabetes and Digestive and Kidney Diseases), and the American Society for Bone and Mineral Research.

Research & Funding

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  • Skeletal Health in Type 1 Diabetes and the Role of Diabetic Kidney Disease
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    Sep 2020
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    Jul 2024
    Principal Investigator
  • Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery
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    Jun 2020
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    Jun 2024
    Principal Investigator (MPI)
  • FSH - an Aging Hormone?
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    Feb 2019
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    Jan 2024
    Subaward PI
  • Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton
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    Mar 2016
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    Feb 2021
    Principal Investigator
  • Prebiotic Intervention to Improve Calcium Absorption After Gastric Bypass Surgery
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    Jul 2017
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    Mar 2019
    Principal Investigator
  • Effects of Gastric Bypass Surgery on Calcium Metabolism and the Skeleton
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    Apr 2011
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    Jun 2016
    Principal Investigator

Clinical Trials

Data provided by UCSF Profiles, powered by CTSI

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 77
Data provided by UCSF Profiles, powered by CTSI
  1. Tiffany Y. Kim, Anne L. Schafer. Chapter 59 Bariatric surgery, vitamin D, and bone loss. Feldman and Pike's Vitamin D. 2024 Jan 1; 161-184. View in PubMed
  2. Wu PH, Joseph G, Saeed I, Pirmoazen AM, Kenny K, Kim TY, Schafer AL, Schwartz AV, Li X, Link TM, Kazakia GJ. Bone marrow adiposity alterations in type 2 diabetes are sex-specific and associated with serum lipid levels. J Bone Miner Res. 2023 Oct 30. View in PubMed
  3. Eileen H Koh, Susan K Ewing, Sigurdur Sigurdsson, Vilmundar Guðnason, Trisha F Hue, Eric Vittinghoff, Mone Zaidi, Clifford J Rosen, Claes Ohlsson, Louise Grahnemo, Åsa Tivesten, Ann V Schwartz, Anne L Schafer. FRI675 Higher FSH Level Is Associated With Increased Risk Of Incident Hip Fracture In Older Adults, Independent Of Sex Hormone Levels. Journal of the Endocrine Society. 2023 Oct 5; 7(Supplement_1):bvad114.443. View in PubMed
  4. Giustina A, di Filippo L, Facciorusso A, Adler RA, Binkley N, Bollerslev J, Bouillon R, Casanueva FF, Cavestro GM, Chakhtoura M, Conte C, Donini LM, Ebeling PR, Fassio A, Frara S, Gagnon C, Latella G, Marcocci C, Mechanick JI, Minisola S, Rizzoli R, Santini F, Shaker JL, Sempos C, Ulivieri FM, Virtanen JK, Napoli N, Schafer AL, Bilezikian JP. Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis. Rev Endocr Metab Disord. 2023 Sep 04. View in PubMed
  5. Link TM, Schafer AL. Bariatric Surgery Negatively Impacts Bone Health in Adolescents. Radiology. 2023 06; 307(5):e231260. View in PubMed
  6. View All Publications

 

 
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