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Anne Schafer, M.D.

Anne Schafer, M.D.

Assistant Professor
Department of Medicine - VAMC

Contact Information

4150 Clement Street
San Francisco CA 94121
Phone 415-221-4810x4895
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  • UCSF School of Medicine, M.D., 2004
  • Internal Medicine, UCSF
  • American Board of Internal Medicine - General
  • American Board of Internal Medicine, Endocrinology, Diabetes and Metabolism Subspecialty
  • UCSF Department of Medicine
  • UCSF Bariatric Surgery Program
  • Dr. Schafer is Assistant Professor of Medicine and of Epidemiology & Biostatistics at UCSF and a practicing endocrinologist at the San Francisco VA Medical Center. She is board-certified in by the American Board of Internal Medicine in Internal Medicine and by the American Board of Internal Medicine in Endocrinology, Diabetes and Metabolism Subspecialty.

Her research focus is on osteoporosis and metabolic bone disease. One of her specific research emphases is osteoporosis treatment and the assessment of response to osteoporosis therapy. Pharmacologic treatment for osteoporosis may involve the use of an antiresorptive agent (one that decreases bone resorption) or an anabolic agent (one that stimulates bone formation). Dr. Schafer and colleagues conducted a randomized, placebo-controlled trial testing two innovative combinations of concurrent and sequential anabolic and anti-resorptive therapy in postmenopausal women with low bone mass. Findings from the trial may help to expand treatment options for osteoporosis. Additionally, Dr. Schafer is actively engaged in research involving the relationship between bone and fat. Bone-fat interplay—including the effects of fat on bone metabolism and the skeletal regulation of energy metabolism—is an area of increasing investigation. Currently, she is studying the effects of bariatric surgery (surgical weight loss) on calcium metabolism and skeletal health. Her research is funded by the U.S. Department of Veterans Affairs, the National Institutes of Health (National Institute on Diabetes and Digestive and Kidney Diseases), and the American Society for Bone and Mineral Research.

Most recent publications from a total of 56
  1. Kim TY, Shoback DM, Black DM, Rogers SJ, Stewart L, Carter JT, Posselt AM, King NJ, Schafer AL. Increases in PYY and uncoupling of bone turnover are associated with loss of bone mass after gastric bypass surgery. Bone. 2020 Feb; 131:115115. View in PubMed
  2. Hindi SM, Vittinghoff E, Schafer AL, Silverman S, Bauer DC. Commercial Laboratory Reproducibility of Serum CTX in Clinical Practice. JBMR Plus. 2019 Oct; 3(10):e10225. View in PubMed
  3. Lyo V, Schafer AL, Stewart L. Roux-en-Y gastric bypass is a safe and effective option that improves major Co-Morbidities associated with obesity in an older, veteran population. Am J Surg. 2019 Oct; 218(4):684-688. View in PubMed
  4. Alliston T, Schafer A. Bone Quality Sleuths: Uncovering Tissue-Level Mechanisms of Bone Fragility in Human Type 2 Diabetes. J Bone Miner Res. 2019 Jul; 34(7):1189-1190. View in PubMed
  5. Niu A, Carpenter TO, Grams JM, Bozorgmehri S, Tommasini SM, Schafer AL, Canales BK. High dose vitamin D supplementation does not rescue bone loss following Roux-en-Y gastric bypass in female rats. Bone. 2019 Oct; 127:172-180. View in PubMed
  6. Zahner GJ, Ramirez JL, Spaulding KA, Khetani SA, Gasper WJ, Grunfeld C, Hills NK, Schafer AL, Grenon SM. Leptinemia is Associated With Peripheral Artery Disease. J Surg Res. 2019 Jun; 238:48-56. View in PubMed
  7. Alba DL, Wu L, Cawthon PM, Mulligan K, Lang T, Patel S, King NJ, Carter JT, Rogers SJ, Posselt AM, Stewart L, Shoback DM, Schafer AL. Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery. J Clin Endocrinol Metab. 2019 03 01; 104(3):711-720. View in PubMed
  8. Hicks GE, Shardell MD, Miller RR, Eastlack M, Orwig DL, Goodpaster BH, Chomentowski PJ, Hochberg MC, Rathbun AM, Cauley JA, Harris T, Satterfield S, Schafer AL, Magaziner J. Trunk Muscle Composition 2 Months After Hip Fracture: Findings From the Baltimore Hip Studies. Arch Phys Med Rehabil. 2019 Sep; 100(9):1663-1671. View in PubMed
  9. Kim TY, Bauer DC, McNabb BL, Schafer AL, Cosman F, Black DM, Eastell R. Comparison of BMD Changes and Bone Formation Marker Levels 3 Years After Bisphosphonate Discontinuation: FLEX and HORIZON-PFT Extension I Trials. J Bone Miner Res. 2019 May; 34(5):810-816. View in PubMed
  10. Ramirez JL, Khetani SA, Zahner GJ, Spaulding KA, Schaller MS, Gasper WJ, Hills NK, Schafer AL, Grenon SM. Serum resistin is associated with impaired endothelial function and a higher rate of adverse cardiac events in patients with peripheral artery disease. J Vasc Surg. 2019 02; 69(2):497-506. View in PubMed
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